President Trump expected to end program for young immigrants

first_img September 4, 2017 Categories: Local San Diego News FacebookTwitter KUSI Newsroom, KUSI Newsroom Updated: 2:21 PMcenter_img Posted: September 4, 2017 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI) — For close to a million children of undocumented immigrants, the halt to the federal government’s DACA program could mean restricted access to higher education and employment opportunities and the possibility of deportation from the United States.  The 2012 executive order signed by President Barack Obama, called “Deferred Action for Childhood Arrivals” — or DACA — allowed young people who were brought to the United States illegally as children to stay in the country, to study or work without the threat of deportation.President Donald Trump is expected to announce Tuesday that he will end DACA in six months, giving Congress the time to replace the executive order with formal legislation that would preserve those protections for the young people who have been called “Dreamers” after the Dream Act which was previously introduced in Congress in several forms, but never passed.If the current Congress fails to act, an estimated 800,000 people who qualified for the DACA program could face the possibility of deportation. Benjamin Prado, an immigration rights activist with the American Friends Service Committee in San Diego fears that “Dreamers” and their entire families will be targeted for deportation.“What we see is the way many immigration agencies do their jobs; they not only go after the individual that they’re looking for but then they start questioning the rest of the family. They start what they consider collateral arrests. That’s why it’s very important, now more than ever, that people understand clearly what their constitutional rights are and that they defend their families,” Prado said.The president of San Diego State University, Sally Roush has written a letter to the White House asking President Trump to retain the DACA program.The letter read in part,  “We urge you to give greatest weight to the fact that these individuals who arrived in this country too young to have made the decision to come here, or to have understood any consequent impact on their citizenship, have in fact excelled as students and as good citizens.”  More than 400 American business leaders, including the CEO’s of AT&T, Best Buy, Amazon, Facebook and Apple have signed a letter to President Trump calling for the DACA program to be retained.They assert that the U.S. economy could lose $460 billion and $25 billion in Social Security and Medicare tax contributions.  President Trump expected to end program for young immigrantslast_img read more

Uptown Ventures Buys Hype Hair Launches U Brands

first_imgUptown Ventures Group acquired Hype Hair magazine, an African American women’s hair care brand, and announced the formation of U Brands, an investment vehicle focused on acquiring and licensing similar niche brands.“We see this as an opportunity to transform brands that have considerable equity and audience into more diverse products with more dynamic P&L’s,” says Brett Wright, chief creative officer of Uptown Ventures, parent company of Uptown Magazine, in a release.Hype Hair magazine is Uptown Ventures’ first acquisition since Uptown Magazine was reacquired from its former private equity partners. The publication’s entire current staff, including its long-time publisher, Steve Gross, and editor-in-chief, Adrienne Moore, will remain with the brand.“Hype Hair has a tremendous relationship with its readers,” says Len Burnett, Uptown Ventures co-CEO, in a statement. “Advertising in credible, well-targeted magazines is the cornerstone of an effective integrated marketing campaign.” These new integrated advertising opportunities in print, digital, on social media and via events-based marketing are the goal of the U Brands venture. With U Brands, Uptown Ventures hopes to leverage its internal capabilities in publishing, digital, experiential, licensing and sales expertise to enhance the brands they acquire.With Hype Hair, Uptown Ventures hopes to launch new digital mobile and social platforms by year’s end in an effort to aggregate the disparate hair care content platforms for the African American community and to offer consumers and advertisers new technologies.last_img read more

Wilmington To Host Lobstah Roll International Roller Derby Tournament On March 910

first_imgWILMINGTON, MA — Boston Roller Derby has announced its first ever international tournament, the 2019 Lobstah Roll.Sanctioned by the Women’s Flat Track Derby Association, the tournament will take place on March 9-10 at the Shriners Auditorium (99 Fordham Road) in Wilmington.The 2019 Lobstah Roll will feature two full days of competition from across the U.S. and Ireland. BRD’s all-star team, the Boston Massacre, will be making their 2019 season debut after winning gold in the WFTDA Continental Cup East last summer. The team currently ranks as No. 34 in the Women’s Flat Track Derby Association out of over 400 internationally affiliated teams.The final two March 9 bouts will be open to the public, with doors opening at 4 p.m. At 5 p.m., the Naptown Tornado Sirens of Indianapolis will take on the Capital Maulstars of Sacramento, California. At 7 p.m., the Boston Massacre will face off against the “A”- team from Dublin, Ireland. All fans will be invited to join skaters for an after-party at 9 p.m. in the Shriners Fez Room, located inside the auditorium.Tickets for Saturday, March 9 can be purchased HERE. For more information on the 2019 Lobstah Roll, visit http://bostonrollerderby.com.(NOTE: The above press release is from the Boston Roller Derby, first published in the Wilmington Advocate.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… Related5 Things To Do In Wilmington This Weekend (March 8-10)In “Community”5 Things To Do In Wilmington On Saturday, March 9, 2019In “5 Things To Do Today”5 Things To Do In Wilmington On Sunday, March 10, 2019In “5 Things To Do Today”last_img read more

Kamal sends letter to PM seeking dialogue again

first_imgPrime minister Sheikh Hasina and Kamal HossainJatiya Oikya Front chief Kamal Hossain sent another letter to ruling Awami League president and prime minister Sheikh Hasina on Sunday seeking the second phase of talks with her over the next general election, reports UNB. Three Gano Forum leaders—Jaglul Haider Afrik, AHM Shafiq Ullah and Mostak Ahmed—carried the letter to Awami League President’s Dhanmondi office around 12:00pm.Talking to UNB, Mostak Ahmed said they handed over the letter to an office assistant, Masud Alauddin.In the letter he said, Kamal Hossain urged prime minister to hold a small-scale dialogue with Oikya Front over the next general election.Earlier on Saturday night, a meeting of the alliance’s steering committee at Kamal Hossain’s Motijheel chamber decided to send the letter to the prime minister.After the meeting, BNP secretary general Mirza Fakhrul Islam Alamgir said, “Jatiya Oikya Front had a dialogue with her (PM) on 1 November, and it was discussed that a small-group dialogue with us can be held again. Based on that, the prime minister will be given another letter tomorrow, Sunday.”In the letter, he said, they will mention about the Oikya Front’s letter sent to the Election Commission urging it not to announce the election schedule until the dialogue is over.Fakhrul hoped that the talks will be held on a small-scale on the country’s current political crisis.Earlier, Kamal, on behalf of the Oikya Front, sent a letter to the Election Commission urging it not to announce the schedule for next election until the ongoing dialogue ends.On 1 November, a 23-member delegation of 14-party, led by Sheikh Hasina, sat in talks at Ganabhaban with Kamal Hossain-led 20-member Oikya Front team.After the meeting, Oikya Front leaders said they placed their seven-point demand before prime minister Sheikh Hasina but did not find any specific solution except some good words about rallies and meetings.Sheikh Hasina invited the Oikya Front leaders to join the dialogue on 29 October following a letter sent to her by Kamal Hossain on behalf of the alliance, seeking talks on election issues.last_img read more

INTERACTIVE MAP Much Of Houston Waits Months For Illegal Dump Site Cleanup

first_img[Click the map to see the average time it took to respond to an illegal dumping call in each city council district. Map by Eric Stone/Houston Public Media]The city of Houston aims to respond to 3-1-1 calls about illegal dumping within 29 days. But it missed that target more often than not in 2018 — it only resolved about 35 percent of dumping complaints on time, according to data from the city’s 3-1-1 website, analyzed by News 88.7.About 65 percent of complaints went overdue – sometimes languishing for well over a month. More than 10 percent of cases took over six months to resolve. The situation is worse in poorer city council districts, especially District D and District I, which are two of Houston’s poorest districts by median household income.In District I, 82 percent of calls went overdue last year and the average claim took 117 days to resolve. That includes Hobby Airport, the East End and Downtown.In Pecan Park, the average claim took over five months to resolve — the longest response time of any of Houston’s super neighborhoods. It wasn’t hard to find an illegal dump site littered with household garbage, including fast food packaging, cans and plastic bags.Eric Stone/Houston Public MediaHousehold garbage litters this illegal dump site in Pecan ParkA check of Houston’s 3-1-1 website, revealed another illegal dump site not far away in Magnolia Park. Hidden on a side road without heavy traffic, more than a dozen tires lined both sides of the road. Among the tires were five-gallon buckets that at one point contained brake fluid, joint compound and hydraulic oil, along with some other household garbage. The vast majority of the mess, though, appeared to be waste from a construction or auto repair business — not a household. The dump site was reported to the city in January, but the refuse remains.Eric Stone/Houston Public MediaCommercial waste, including tires, buckets of oil and cans of brake fluid, line Brays Road in Magnolia Park.In District D, which includes the Third Ward and Sunnyside, 78 percent of complaints went overdue. Lee Simmons grew up in the Third Ward, and he expressed frustration with the city’s response to illegal dumping.“It’s almost like they never come. I see a lot of trash and it just sits there,” Simmons said. On average, it takes the city 107 days to respond to complaints in District D.[This map shows the city’s response to illegal dumping complaints broken out by super neighborhood, as defined by the city. Map by Eric Stone/Houston Public Media] Sharelast_img read more

Typical Casino Patrons Have Solid Careers Better Education

first_imgThe HorseShoe Casino Baltimore will stage its grand opening, Aug. 26, welcoming an estimated 10,000 guests through its doors.Over time, however, the casino’s patrons will not be distinguished so much by race but by income and education, experts said.“There is not much data on the racial breakdown of casino-goers,” said gambling expert James KarmelIn terms of general gambling patterns, Whites are more frequent gamblers (92.5 percent), followed by African Americans (87.5 percent) and Hispanics (86.6 percent), according to a 2011 study by researchers at the University of Maryland, Baltimore County.However, when it comes to the subset of casino gamblers, there are much clearer distinctions based on education and income,Karmel added.“Casino-goers tend to be slightly more educated that non-Casino-goers. And, typically, casino gambling is associated with income.For the vast majority of people, gambling at casinos is a recreational activity; they’re doing it with disposable income, money they can afford to spend,” Karmel, a professor of history at Harford Community College, said.“You just don’t find a lot of poor people in casinos,” he added. “People at lower income levels can’t afford to lose $50; they need that for food.”However, poorer Americans—who tend to prefer gambling closer to home—are more likely to spend their income on lottery games, as are African Americans.“Lottery is more dependent on lower-income people [and] African Americans are somewhat more likely to gamble on the lotterythan Whites,” Karmel said.Those assertions were borne out in a 2010 study conducted by UMBC researchers.Published in The Journal of Gambling Business and Economics, the study titled “Who Pays for Maryland Lottery? Evidence fromPoint of Sale Data” married lottery terminal locations with Census tract data and examined the results using geographic information system maps to explore how racial and income groups contribute to state lottery revenues.The findings showed “the voluntary tax collected by the Maryland lottery comes disproportionately from census tracts populatedby African Americans and low-income residents,” specifically those “with less than a high school education, and people age 65 andolder.”Again, with regards to casino gaming, even as city officials, casino owners and gambling aficionados welcome the new parlor, African Americans are more vulnerable to some of the ills of gambling.According to the 2011 UMBC study, “Gambling Prevalence in Maryland: A Baseline Analysis,” which was commissioned by Maryland’s Department of Health and Mental Hygiene, African Americans are 12.5 percent at risk of becoming problem gamblersand have a 4.9 percent rate of pathological gambling.Comparatively, Whites are less likely to be at risk of developing problem gambling at 8.2 percent, and experience a mere 2 percent of pathological gambling concerns.last_img read more

Women across decades

first_imgStree presents a broad range of over 300 works from Swaraj Art Archive exploring the female form as perceived by both male and female artists spanning from the pre-independence to the post-independence era. The event begins from January 23 onwards and will be held at the Swaraj Archive, Sector 2, Noida. Divided into five categories, the exhibition is spread across mediums representing the woman as an emotion – harmony; love; pride; devotion; and acquiescence; throwing light on the stylistic differences in artists’ expression conveyed by the female form. Also Read – ‘Playing Jojo was emotionally exhausting’It includes works by about 100 artists, from Kalighat painters to Arpana Caur, whose names will not be disclosed on the walls, allowing the observer to walk through the show unaccompanied by the predisposition associated with the identity of an artist. The show provides a visual comparative of the iconography associated with each of the above emotions showcasing the depth of Indian art from the 1850’s to now.Every artist possesses an individual artistic sensibility which, when driven by raw emotion, truly manifests into his creation, affecting the form, composition and its dialogue with the observer. Also Read – Leslie doing new comedy special with NetflixDivided into five sub-concepts, the exhibition spreads across time, mediums, scales and histories representing the woman as an expression of an emotion.The exhibition comprises over 300 works representing the ‘woman’ as an expression of an emotion. Providing a visual comparative of the iconography associated with each of the emotions – Harmony, Love, Pride, Devotion and Acquiescence – the collection showcases the depth of Indian art from the 1850’s to the present. This Exhibition aims to show the depth of Indian Art in its entirety. The non-chronological display of the artworks, segregated via emotions, which translate themselves into certain physical decipherable forms, allows the viewer to read and dwell into the art itself, rather than assess it pragmatically based on market researches associated with specific artists. A small effort has been made with this exhibition for the art to speak for itself without being weighed down or enhanced by the artists’ biographies. The viewer will then experience art without judgment and/or in comparison to the plethora of stylistic languages through Indian Art.last_img read more

Microsoft brings PostgreSQL extension and SQL Notebooks functionality to Azure Data Studio

first_imgMicrosoft announced the March release of Azure Data Studio, yesterday. This latest Azure Data Studio release explores features such as preview support for PostgreSQL in Azure Data Studio,  corresponding preview PostgreSQL extension in Visual Studio Code (VS Code), and SQL Notebooks, among others. What’s new in Azure Data Studio? PostgreSQL extension for Azure Data Studio There’s new preview support for PostgreSQL in Azure Data Studio. The preview support adds on-premises and Azure Database for PostgreSQL to its existing support for SQL Server, Azure SQL Database, Azure SQL Managed Instance, Azure SQL Data Warehouse, and SQL Server 2019 big data clusters. The Azure Data Studio extension for PostgreSQL comprises a Tools API service that offers data management and high performant query execution capabilities. Azure Data Studio also provides a modern, keyboard-focused PostgreSQL coding experience, that simplifies your everyday tasks. Users can also run on-demand SQL queries now such as the view and save results as text, JSON, or Excel. There’s also an extension marketplace for Azure Data Studio for developers that help them build and contribute back into the open source ecosystem. Microsoft team states that it is making the new PostgreSQL extension experience open source under the MIT license. This will allow the users to connect to all PostgreSQL databases in case they’re running on Azure (Azure Database for PostgreSQL). SQL Notebooks Using SQL Notebooks, you can easily interleave the written instructions, analysis, diagrams, and the animated GIFs using markdown. You can then add code cells with the SQL code to be executed. The SQL Notebook functionality has been built into the base of Azure Data Studio product and requires no additional extensions to connect to servers and execute the SQL result sets. These SQL notebooks can be used like any other regular query editor. You can get started with SQL notebooks just like a regular query editor. In case you’d like to use other languages such as Python, R, or Scala, you’ll be prompted to install other additional dependencies. PowerShell extension PowerShell extension from Virtual Studio (VS) Code is now featured in the Azure Data Studio marketplace. The new PowerShell extension aligns with the other automation scenarios used by the database administrators and developers. There’s an integrated terminal in Azure Data Studio that makes it easy for users to integrate PowerShell experiences with data. SQL Server dacpac extension Microsoft team mentions that it has been trying to improve the Data-Tier Application Wizard in Azure Data Studio after receiving feedback from the community. Originally shipped with the SQL Server Import extension, this feature will now be shipped as a separate extension. This is because the team plans to bring more features making it easy to use dacpacs and bacpacs in Azure Data Studio. This extension will also be included in the Admin pack for SQL Server, an extension pack that lets you quickly download the popular features from SQL Server Management Studio. Other Changes Community extension highlight: Queryplan.show The Queryplan.show extension adds integration support to visualize query plans using the community extension Queryplan.show. Visual Studio Code Refresh from 1.26.1 to 1.30.2 There have been a few refresh updates from the July release (1.26.1) to the November release (1.30.2) of VS Code. Highlights are as follows: New Settings editor UI making it easy to modify Azure Data Studio settings. Multiline search improvements. Better macOS support. SQL Server 2019 Preview extension The Microsoft team has been moving features from the SQL Server 2019 preview extension into the core Azure Data Studio tool for decades now. Here is a summary of the features moved into the core tool: Jupyter Notebook support has been moved to Azure Data Studio. Bug fixes in the External Data wizards: New schemas typed into the table mapping controls were getting lost. This is fixed now. Oracle type mappings have been updated. For more information, check out the official March release notes for Azure Data Studio. Read Next Microsoft Azure reportedly chooses Xilinx chips over Intel Altera for AI co-processors, says Bloomberg report Microsoft Azure now supports NVIDIA GPU Cloud (NGC) Microsoft Azure’s new governance DApp: An enterprise blockchain without mininglast_img read more

Drilling Intersects 102 Meters of 197 gpt Gold at

first_imgDrilling Intersects 102 Meters of 1.97 gpt Gold at Columbus Gold’s Paul Isnard Gold Project; Drilling Confirms Depth Extension of Gold MineralizationColumbus Gold Corporation (CGT: TSX-V) (“Columbus Gold”) is pleased to announce results of the initial five (5) core drill holes at its Paul Isnard gold project in French Guiana. The holes confirm depth extension of gold mineralization below shallow holes drilled on the 43-101 compliant 1.9 million ounce Montagne d’Or inferred gold deposit at Paul Isnard in the 1990’s and support the current program of resource expansion through offsetting open-ended gold mineralization indicated by the earlier holes.Robert Giustra, CEO of Columbus Gold, commented: “These drill results validate Columbus Gold’s approach to adding ounces with a lower-risk drilling program designed to infill and to extend the mineralized zones to 200 m vertical depth from surface; a depth amenable to open pit mining.”  Fourteen (14) holes have been completed (assays pending) by Columbus Gold in the current program and drilling is progressing at the rate of about 3,000 meters per month with one drill-rig on a 24 hour basis. Columbus Gold plans to accelerate the current program by engaging a second drill-rig as soon as one can be obtained. Please visit our website for more information about the project. It was more than obvious [at least to me] that a heavy hand showed up in these markets at, or just before, the London p.m. gold fixGold didn’t do a lot on Tuesday, either.  The rally that developed in early Far East trading, ran into a seller just before 11:00 a.m. Hong Kong time…which was the same thing that happened during the Monday trading session.From there, the gold price didn’t do much until the 8:20 a.m. Eastern Comex open.  At that point the dollar index cratered…and gold took off…running into a not-for-profit seller at the London p.m. gold fix which came shortly after 10:00 a.m. in New York.  The high tick at the ‘fix’ was $1,739.10 spot.Despite the fact that the dollar continued to decline, the gold price continued to get sold down until around lunch time on the East coast…and from there traded sideways into the 5:15 p.m. electronic close.Gold finished the Tuesday session at $1,732.50 spot…up only $7.70 on the day.  Net volume was the same as Monday’s…115,000 contracts.It was basically the same story in silver as well, except for the fact that the rally at the Comex open was so strong, that a not-for-profit seller had to enter the market around 9:35 a.m. Eastern, or silver would have been materially higher [and well above $34 spot] by the London gold fix, which occurred thirty minutes later.  The high tick of the day at that point was $33.95 spot.And, like gold, despite the fact that the dollar index was declining steadily, silver continued to get sold off to its New York low…$33.30 spot…which came about 3:20 p.m. in electronic trading.  The price recovered a hair into the close.Silver finished the day at $33.48 spot…up a meager 14 cents from Monday.  Volume, 38,000 contracts, was down quite a bit from Monday’s 48,500 contracts…but still very high.Without doubt, both gold and silver would have finished materially higher if a willing seller hadn’t show up at, or just before, the London p.m. gold fix in both metals…and it was precisely the same story in platinum and palladium as well.The dollar index opened around the 80.40 mark on Monday evening…and chopped around that point until about 3:20 p.m. Hong Kong time, or about forty minutes before the 8:30 a.m. BST London open.  During the next hour, the index dropped a bit over 20 basis points…and then more or less traded sideways until 8:30 a.m. in New York.  Then the index headed south with a vengeance…and by 11:30 a.m. Eastern, the dollar index had shed another 40 odd basis points to its low of the day, which was around 79.82…and then recovered a handful of basis points going into the close.  The dollar closed down 50 points on the day at 79.89.If you check all four precious metal charts from yesterday, you’ll note that all had a very positive reactions to the pre-London open dollar index decline.  And that state of affairs continued in New York when the index did another face plant starting around 8:30 a.m. Eastern.  All the precious metals took off to the upside…and all ran into the same not-for-profit seller at the London p.m. gold fix…except for silver.As I said further up, its rally was so strong, it had to be dealt with early, or it would have blasted through the $34 spot price like a hot knife through soft butter…and that was obviously not going to be allowed…just like it wasn’t allowed in early morning trading in Hong Kong on Monday.  Check the silver chart above for the details.From the London p.m. gold fix, until the dollar index nadir at 11:30 a.m. Eastern, the dollar index and the precious metals prices all declined together.  That’s just too cute for words.There are no market anymore…only interventions.Although the gold price hit its zenith shortly after 10:00 a.m. Eastern time, the shares powered a bit higher, hitting their high of the day around 11:30 a.m. Eastern…which was the dollar index low.  After that they went into decline but, like Monday, finished just off their lows…and the HUI closed up 0.55%.  Excuse me for thinking out loud at this point, but the saw-tooth pattern to this chart tells me that someone with a fairly large position appeared to be selling into this rally.The silver stocks finished mixed…and Nick Laird’s Silver Sentiment Index closed up 0.67%.(Click on image to enlarge)The CME’s Daily Delivery Report was rather interesting.  There was no delivery activity in gold, but there were 270 silver contracts posted for delivery within the Comex-approved warehouse system on Thursday.  The only short/issuer was Jefferies…and the biggest long/stopper was, once again, JPMorgan…with 202 contracts in its in-house [proprietary] trading account…and 23 for their client accounts.  The Issuers and Stoppers Report is worth a quick look…and the link is here.There were no reported changes in either GLD or SLV yesterday.Nick Laird advised me that Sprott added another 40,535 troy ounces of gold to their Physical Gold Trust on Monday.  That should just about cover the entire amount received in their follow-on offering…but I expect there’s a bit more when the underwriters exercise their ‘Greenshoe Option’.Over at the U.S Mint, they reported selling another 50,000 silver eagles…and I do hope that you’re getting your share, dear reader.The action at the Comex-approved depositories on Monday is hardly worth mentioning, as only a few thousand ounces of silver were received…and shipped out.I don’t have very many stories today…and that suits me just fine.  I hope you have the time to skim them all.Despite the positive closes in all four precious metals, it was more than obvious [at least to me] that a heavy hand showed up in these markets at, or just before, the London p.m. gold fix at 3:00 p.m. BST…10:00 a.m. in New York.  With the dollar index in free-fall, the precious metals were not allowed to do what they wanted to do…and that is close the day materially higher than they did on Monday.You’re perfectly entitled to your own opinion on this, but that’s the way it appeared to me…and if you have some other explanation for yesterday’s 180 degree move in the precious metals while the dollar index was falling out of bed, I’d love to hear it.Yesterday, at the 1:30 p.m. Eastern time Comex close, was the cut-off for this Friday’s Commitment of Traders Report…and as I’ve been stating all along, it will not make for happy reading…especially with the huge volumes [and price increases] we’ve seen in both gold and silver since last Tuesday’s cut-off on September 4th.  JPMorgan et al are still acting as short sellers of last resort and preventing the precious metal prices from blowing sky high.  I’ll be curious to know how much larger JPMorgan’s short position in silver has become since last Friday’s report.  Ted Butler says it’s north of 27% of the entire Comex futures market in silver on a net basis.  Will it break 30% on Friday?I’m still of the opinion that we’ve seen a short-term top, but would love to be proven wrong.  A quick engineered sell-off by “da boyz” to relieve the current overbought condition wouldn’t bother me in the slightest…and would be a buying opportunity that I would take full advantage of.  Of course if/when the sell-off does come, it will allow these short sellers of last resort to harvest all the new long positions that have been placed and ring cash register one more time.In Far East trading on their Wednesday, both gold and silver prices chopped slowly higher.  For a change, volumes in both metals are significantly lower than they were on either Monday or Tuesday, so I wouldn’t read a whole heck of a lot into the price action.  The dollar index is down about 11 basis points as London opens for trading at 8:00 a.m. local time…3:00 a.m. Eastern.London trading opened quietly, but that all changed around 9:15 a.m. BST, when gold and silver blasted higher in seconds, not minutes.  Gold was up fifteen bucks…and silver shot through $34 spot at warp speed.  The reaction from JPMorgan et al was instantaneous.  Gold volume jumped from 13,000 contracts to 34,000 contracts in a heart beat…and silver’s volume went from around 4,800 contracts to 9,500 contracts in the same period of time…seconds.  Then, after that assault, it appears that another rally is underway…and silver is now back at $34.00 spot once again…and gold is struggling higher.  No ‘for profit’ seller ever sells into a rally like that…EVER!!!  This is in-your-face price management by the bullion banks…and the farthest thing from a free market that one can imagine.  It was obvious that ‘da boyz’ were lying in wait for this event.Here’s what Kitco’s silver chart looked like at 5:14 a.m. Eastern time…I would guess that this price action was centered around the announcement from the German court…and we’ll probably find out more as the day goes along.Before I sign off today, most of you may already have heard that we have a new writer at Casey Research…and his name is Dennis Miller.  He’s been a regular reader of my column for many years…and now, like me, he’s working for Doug.  Dennis is retired…and has been working tirelessly to rebuild his nest egg since the crash of 2008, when his CDs were recalled and it was cut by 50%.  He’s documented his journey in his book Retirement Reboot…and he thinks highly enough of what I’ve had to say over the years, to mention my name in a couple of places in it.  The book is priced at a pittance…a mere $9.95…and you can find all about it here.  It costs nothing to check it out.It could be an interesting day during Comex trading in New York today.See you tomorrow. 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In This Issue   Currency metals rally but in

first_imgIn This Issue. *  Currency & metals rally but in a tight range. *  NZ Unemployment Rate drops to 6.2%! *  Australia’s Trade Deficit shrinks. *  That’s 5 Fed Heads wanting to extend stimulus. And, Now, Today’s Pfennig For Your Thoughts! Another Fed Head Has An Epiphany! Good day.  And a Wonderful Wednesday to you! I just realized something, that I guess I’ve known for a long time, but just registered it in my mind. I love the smell of blueberries! I opened the package for a Blueberry cereal bar, and there it was! The wonderful blueberry aroma! My mind immediately flashed back to when I was a young boy and would spend weeks of summer on my grandparents farm, and we would be sent out to gather the berries. My grandma had blueberries, blackberries, raspberries and other stuff that she always used in baking. But we would get some of the fresh berries, run the cistern water from the well over them and have ourselves a treat! Sorry to go off on that tangent, but it’s just another example of my stream of thought. Yesterday I left you with the thought that only a few currencies were gaining VS the dollar, and Gold was down $2. But soon after I sent the letter out, the currencies rebounded, along with Gold. Chris called me, (he’s out of town) and wanted to know what was going on, and I told him that the turnaround was interesting in that there wasn’t anything to cause it, the U.S. data wasn’t out yet, and the only thing I saw was data from the UK that showed that the servicing industry had expanded in October.  The rest of the day though, the currencies and metals were stuck in the mud. Funny, thing, when I was 18 and traveling around the country with my guitar, my friend, and our drummer, Preston, used to call people my age now, “old sticks in the mud”. And that pretty much describes the currencies yesterday, overnight and into this morning. sticks in the mud.   Recall yesterday that I told you the New Zealand dollar / kiwi was the best performing currency overnight as traders were thinking that the labor report that was due to print that afternoon, would be strong, and that usually meant good things for kiwi. Well, it appears that the traders were rewarded for their foresight, as New Zealand’s Labor report was even better than forecast! The consensus going into the report was for a drop in the Unemployment Rate from 6.4% to 6.3%, but in the 3 months ending September 30th, the New Zealand Unemployment Rate actually fell to 6.2%! The Labor report really placed kiwi firmly on the rally tracks, and this morning, the currency is trading at a 6-week high, as everyone and their brother now expects the Reserve Bank of New Zealand (RBNZ) to hike rates early next year. Another component of the report showed that Ordinary Time Private Sector Wages rose 1.6% in the quarter and up 2.6% year-on-year!  Can you say “inflation problems are coming?” I knew you could! And maybe, just maybe, because you never know, the RBNZ will hike rates before early next year! Well, since the middle of last week, the euro has been on the slippery slope for a few reasons that we’ve talked about, but the reason that has weighed the most on the euro, has been the drop in inflation in the Eurozone, which brought the rate cut campers out of the woodwork. But as I explained two times already, but will do it again for those that missed class those days. I don’t see the benefits to cutting rates when they are already at all-time lows.  And believe it or don’t, the markets are beginning to come around to Chuck’s way of thinking. Now, that would be a story! I can see the headline: Market Comes Around To Chuck’s Way of Thinking.  And the reporter would ask the first question. “Now Chuck, what do you think the ECB will do?”  OK, if you’re not laughing with me, you’re laughing at me! Stop that! Another currency that was showing a gain yesterday morning, and is pumping out an even larger gain overnight is the Swedish krona. In just a few hours we’ll see the color of the last Riksbank (Central Bank) meeting, and the markets believe they’ll be able to find indications that the Riksbank is ready to hike rates. That thought has the krona hitting on all 8 this morning. Hey! Another U.S. Fed Head had his epiphany about the economy yesterday. San Francisco Fed President, John Williams, fessed up about the economy saying that, “Up until recently, I was thinking we would start seeing more of that self-powered growth in the second half of this year. Unfortunately, that’s not really been happening and we haven’t seen a real pickup. We’re still a long ways from where we want to be.” So. It’s apparent that the economic growth that Williams was looking for has fallen short of his expectations, and now he’s losing faith that the labor markets’ gains will endure without monetary stimulus..  Of course, the 3 Fed Heads we talked about yesterday, and now Williams only had to read the Pfennig many months ago to know that I said they were being over optimistic about the economy, and maybe they would have tempered their exuberance about the economy. And then we wouldn’t have had the Taper Capers, spoil the currency & metals soup. But then, I still think that Big Ben and the Fed Heads (sounds like Frankie Valli and the 4 Seasons!)  were simply attempting to let some air out of the stock market bubble that they created with all this stimulus, by talking about Tapering. I’m writing this morning, while listening to Led Zeppelin’s all-time best song. Kashmir. Now that’s a song that needs the volume cranked to 10!  Hey. I just saw something on the TV that shocked me. They showed a survey result that shocked me! 34.3% of Americans say they don’t want a job!  And apparently, the total of Americans wanting to have a job has been declining since 1980! That’s not a good thing for us Baby Boomers who have either already retired, like 90% of my classmates that attended my 40th H.S. reunion, or starting to prepare to retire. Oh, the things that I see, hear & read about that make my skin crawl!  But you know what I’ve finally realized? That while I can write about it, and attempt to get people to think about these things, I can’t change them. I used to have these thoughts that if I wrote about something that was wrong that people would read it, think about it, and do something like call their representative or whatever, and that would eventually change things!  Yes, Virginia, there is a Santa Claus. Hey! Down Under in Australia, where they are enjoying spring, their Trade Deficit came in better than expected for September, printing at A$ 284 million, VS A$ 500 million expected. And the August total was revised downward. The Aussie dollar (A$) is back above 95-cents, and looking forward to the latest Employment Report that will print tonight. I would look for an increase in jobs for October, and that should support this latest uptick in the A$. The A$ deserves some lovin’, after taking body blows from the Reserve Bank of Australia (RBA) Gov. Stevens last week and this week. This has my spider sense tingling folks. You don’t think that Stevens knew ahead of time that the data was going to be good this week, and went about verbally assaulting the A$, getting it weaker, ahead of the data?  Nah. that would be giving too much credit to a Central Banker, and I’m tough when it comes to grading! In the UK, the pound sterling has really been a roll this week. First it was the strong servicing Index performance, and today it was a strong Industrial Production print that pushed the pound sterling to 1.61. Industrial Production pushed higher to a gain of .9% in September, up from the August negative print of -1.1%…  In addition, Home Prices showed their biggest gain (+.7%) in 3 months.  The Bank of England (BOE) meets tomorrow, right after these strong economic data prints, but I doubt it will move the BOE to change rates from their near zero level, or change their bond buying program. And that’s why I still don’t think the pound has strong legs to take it from here. If the BOE still believes that near zero rates and bond buying is needed, then they are a country mile away from hiking rates, which I believe will be needed to take the pound higher from here. But that’s just my opinion and I could be wrong! I see where the Chinese decided that two days of gains in their currency the renminbi / yuan, was enough, and they weakened the fixing level overnight.  I read a story on the Bloomberg that talked about how the Chinese fear that the Fed will begin to taper in December. Hey! Here’s a Memo to China. Don’t worry about tapering. 4 Fed Heads this week have pretty much put the kyboshes on tapering any time soon, and don’t forget that a 5th Fed Head, Evans, laid out the scenario where tapering would never happen. I was looking at Google+ last night and came across a posting that someone made that reminded me of the slide that Frank and Chuck use in presentations that show men that have painted themselves into corners.  This posting had just one person that had painted themselves into a corner, with a caption that read: Before You Start Anything. Learn How To Finish It! And so it goes with the Taper Capers. Gold is up $6 this morning, with Silver, Platinum and Palladium all posting gains too! But when you step back and look at a chart of these metals, you see that they’ve been range trading for what seems like a month of Sundays.  I read a story by Gold Enthusiast James Turk yesterday, about how the world had reached a tipping point, as the next catastrophe approaches. While I see that certainly capable of happening, I have to stop and remember that it was Turk that said we would have a Black Swan event this year. Remember that? (I guess we just barely averted one with the default last month, eh? ) I know one thing, that it is far better to make your forecasts without giving time frames for them to happen! The U.S. data cupboard has the Leading Index report for September this morning, and that’s it. the Leading Index report has really shifted upward in recent prints, which surprises me a bit, in that usually this is good forward looking data, but I don’t see anything in the economy that leads me to feel warm and fuzzy about an uptick in the leading index report. Before I head to the Big Finish this morning, I have a funny from Jay Leno. “According to a new study out of Harvard, it is easier for people to be moral in the morning. They say people are more moral at the beginning of the day, but they become more dishonest as the day goes on. So when people say Congress is as dishonest as the day is long, we now have scientific proof.” For What It’s Worth. On the heels of the announcement that the CFTC’s Bart Chilton was stepping down, the U.S. derivatives regulator announced yesterday that they plan to curb market speculation in commodities. Here’s a snippet of the story as it appeared on Reuters. “The Commodity Futures Trading Commission  (CFTC) proposal will set caps on the number of contracts that a single trader can hold in energy, metal and agricultural markets, a measure aimed at capping speculation that some blamed for the spike in raw material and food prices prior to the 2008 financial crisis. The redrafted rules sought to answer some of the deficits that a judge pointed out last year. The agency cited two of the biggest cases of market manipulation in history – the Hunt Brothers’ silver corner and hedge fund Amaranth natural gas bet – as evidence of why curbs were necessary. The new rules will also make it easier for big banks such as Goldman Sachs Group Inc and Barclays PLC to remain in the market by allowing them to exclude positions held by entities in which the banks own minority stakes – a key trigger for the banks to sue the agency.” Chuck again. Well, that’s all fine and good, but I doubt it gets past the Bullion Banks that have the large short positions. They’ll take it to court once again, and once again a judge will shoot the CFTC’s regulation down. That’s because as I’ve told you over and over again, this dance is gonna be a drag, no wait! What I’ve told you over and over again is that in my opinion, which was formed by the Wikileaks Cable, the Gov’t is behind all this. And therefore, there will be no regulation that takes away the ability of the Big Bullion Banks to hold short positions in metals that are larger than the size of the market! To recap. The mixed bag of results early yesterday morning for the currencies and metals turned around mid-morning, and gains were eked out VS the dollar on the day, but in the end, these asset classes are stuck in the mud, trading ranges. The BOE & ECB will meet tomorrow, and strong recent data from the UK, has pound sterling rising, but without a rate hike, and there will be none any time soon, the pound has no strong legs to stand on. New Zealand Unemployment Rate drops more than expected, and kiwi is the best performer overnight. Currencies today 11/6/13. American Style: A$ .9525, kiwi .8405, C$ .9570, euro 1.3515, sterling 1.61, Swiss $1.0970, . European Style: rand 10.2110, krone 5.9645, SEK 6.5075, forint 219.70, zloty 3.0845, koruna 19.0825, RUB 32.37, yen 98.65, sing 1.2425, HKD 7.7515, INR 62.40, China 6.1475, pesos 13.13, BRL 2.2835, Dollar Index 80.53, Oil $94.08, 10-year 2.65%, Silver $21.95, Platinum $1,463.68, Palladium $758.58, and Gold. $1,318.34 That’s it for today. A good shootout win for our Blues in Montreal last night, I went to bed and it was tied 2-2. the Blues are off to a good start to the season. Yadier Molina is a finalist for NL MVP, even if he doesn’t win, and he should, but has the “sentiment vote for the Pittsburgh Pirates player” going against him, that’s a great accomplishment for him! Two other Cardinals are finalists, Wainwright for Cy Young, and Miller for Rookie of the year. But I doubt any of them get the final vote. But again that doesn’t take away from their great seasons! Jessie Colin Young and the Youngbloods are singing their 60’s anthem, Let’s Get Together on the IPod right now. That’s a song we used to play!  The swimming season begins to wind down tonight for Alex, with the Conference prelims. Hey! What Day is it? Mike, Mike, Mike, what day is it? Come on, you know. It’s HUMP DAY!    Ok, let’s go have a Wonderful Wednesday and Hump Day! Chuck Butler President EverBank World Markets 1-800-926-4922 1-314-647-3837last_img read more

As I write this paragraph the London open is abou

first_imgAs I write this paragraph, the London open is about 40 minutes away.  The prices of all four precious metals aren’t doing much.  Gold volume is even lower than it was this time yesterday—but silver volume is much higher than it was yesterday at this time, but still very much on the lighter side.  And, not that it matters, but the dollar index is up a half-dozen basis points.There’s not much to add to today’s column, as just about everything worth saying showed up in The Wrap sections of my Tuesday and Wednesday missives—and I’m not happy when I keep repeating myself every day, which is easy to do when there’s not much going on.And as I hit the ‘send’ button on today’s effort at 5:05 a.m. EDT, I see that all four precious metals have rallied above their respective closes in New York yesterday—and it’s obvious that the rally in gold is running into resistance, as the open interest is now more than double what it was 40 minutes before the London open—and even though the rally was only about five bucks, that was obviously too much for ‘da boyz’.  Silver volume is getting up there as well, but it’s still very much on the lighter side, all things considered.  The dollar index is flat.So far, everything is unfolding like it normally does this time of day, as any rally in gold and silver that begins shortly before [or at] the London open, is dealt with before the London a.m. gold fix—and then the rest is left up to JPMorgan et al in New York when the Comex opens.  It remains to be seen if this pattern repeats itself again today.I hope your Thursday goes well, or went well if you live west of the International Date Line—and I’ll see you here tomorrow. Here are two more photographs from my Sunday outing—and both were taken in the same park and from exactly the same spot as the gulls I posted yesterday.  The difference is that these juvenile Black-crowned night herons were over well over 100 metres away across a pond and on an island—and despite using a big telephoto lens, I had to crop the heck of these two photos to get the birds up to this size.  Because of the distance and the cropping, they both fall into what I consider minimum acceptable picture quality, at least for me. The price management scheme in gold is now so obvious, that it’s no longer debatable.Gold did very little in Far East trading and the first half of the London trading day on Wednesday.  The rally at the Comex open wasn’t allowed to get far—and was sold back down to unchanged by noon in New York.  It rallied a few dollars going into the 1:30 p.m. Comex close—and then chopped sideways into the 5:15 p.m. close of electronic trading.The low and high aren’t worth the effort to look up.Gold finished the Wednesday session at $1,312.20 spot, up $3.70 from Tuesday’s close.  Volume, net of August and September, was pretty light at only 104,000 contracts.The silver price followed more or less the same price path as gold, expect the rally at the Comex open got sold down harder—and silver made a new low for this move down—and that low was printed about 11:50 a.m. EDT.  The price rallied a bit going into the Comex close—and the didn’t do much after that.The high and low ticks were recorded by the CME Group as $20.085 and $19.705 in the September contract.Silver closed at $19.81 spot, down 10.5 cents from Tuesday’s close.  Net volume was 33,000 contracts.Platinum didn’t do much of anything in early Far East trading, but developed a positive price bias beginning around 2 p.m. Hong Kong time.  It was up a whole six bucks on the day by shortly before 11 a.m. EDT—and then a thoughtful soul sold it down about a percent, with the low coming minutes before noon in New York.  From there it rallied back to almost unchanged—and down a buck on the day.The price action in palladium was similar, but both the corresponding rally—and subsequent sell-off, were much less pronounced.  Palladium manged to finish up a buck.It was another day where all four precious metals were rallying—and then all got sold off during the New York trading session.The dollar index closed on Tuesday at 81.51—and didn’t do much of anything until shortly after 2 p.m. Hong Kong time.  Then it rallied to its 81.65 high before it had a 25 basis point down/up move between the 8:20 a.m. Comex open and 11:40 a.m. EDT.  After that the index slid a small handful of basis points into the close, finishing at 81.61—up 10 basis points.The gold stocks chopped and flopped either side of unchanged yesterday—and finished the day that way, as the HUI closed down a miniscule 0.05%.The silver equities barely got a sniff of positive territory on Wednesday—and headed lower almost immediately.  The low of the day came at the low for silver, about 11:50 a.m. EDT.  From there they cut their loses by a bit, as Nick Laird’s Intraday Silver Sentiment Index closed down 0.87%.The CME Daily Delivery Report showed that 6 gold and zero silver contracts were posted for delivery within the Comex-approved depositories on Friday.  Nothing to see here.The CME’s Preliminary Report for the Wednesday trading session showed that August open interest in gold declined by 117 contracts—and is now down to 1,167 contracts—so we await the final resolution on this as the month starts to wind down.There was a tiny 8,420 troy ounce withdrawal from GLD yesterday, which was probably a fee payment of some kind—and as of 9:18 p.m. EDT yesterday evening, there were no reported changes in SLV.There was a sales report from the U.S. Mint again yesterday.  They sold 500 troy ounces of gold eagles—500 one-ounce 24K gold buffaloes—225,000 silver eagles—and another 200 platinum eagles.There wasn’t a creature stirring in the gold departments of the Comex-approved depositories on Tuesday.  However, it was another big day for silver, as 600,769 troy ounces were reported received—and 693,508 troy ounces were shipped out the door.  All of the activity was at the CNT Depository—and Brink’s, Inc.  The link to that action is here.I have a very decent number of stories again today—and there should be some in here that interest you.For those with an interest in silver, I believe that a remarkably large percentage, certainly a majority, believes that silver is manipulated in price. They might not be able to articulate all the nuances of the manipulation, but they have a strong sense that there is an artificiality to silver pricing. I base this on what’s said and written on the Internet, of course, not in the main stream media, which continues to treat the topic of manipulation as something to be avoided at all costs. I believe this is the case because the biggest advertisers and commercial supporters of the main stream media tend to be the very financial institutions perpetrating the manipulation.Nowadays, it’s actually more unusual when someone strongly denies the existence of a silver manipulation, particularly if the denier is well known. Invariably, the denial brings an outcry of disagreement to the point of mockery. Not for a minute have I ever concluded that silver is manipulated or not by the weight of popular opinion; for me, the manipulation is quite easily proven by the verifiable facts. My point is simply that more who are interested in silver believe it is manipulated in price, than not.That might not seem like an earth-shaking revelation, but in reality it is very much so from what things once were. A quarter-century ago, very few, if any, believed silver was manipulated in price. I know this to be the case because I lived through it. For better or worse, the idea of a silver manipulation originated with me. I point this out, not to pat myself on the back, but strictly to demonstrate the difference between then and now in popular perceptions. In fact, I think you would be shocked at the degree of resistance that existed to the idea that silver was manipulated back then. – Silver analyst Ted Butler: 13 August 2014It was another day when not much happened during the Wednesday trading session.  It was also another day that the rallies in all four precious metals, such as they were, got sold down during the New York session once again.Here are the 6-month charts for both gold and silver—and nothing much has changed.last_img read more

When humorist and writer Mara Altman was 19 and at

first_imgWhen humorist and writer Mara Altman was 19 and attending college at UCLA, she learned something about herself which, she says, felt devastating at the time.It happened while she was flirting with a server at a Mexican restaurant one evening. His name was Gustavo and he said five simple words: “I like your blonde mustache.”Now, she knew about this blonde mustache. But she had been bleaching it for years in the hopes that no one else would notice it.Altman’s latest book, Gross Anatomy: Dispatches from the Front (And Back), is a personal, darkly witty investigation into the human body — how we think about it and how it works. In a mix of personal anecdotes, science and cultural reporting and interviews, Altman explores pressing questions like, is PMS real? How come some people sweat so much? And who decided women shouldn’t have body hair, anyway?In an interview with NPR’s Ailsa Chang, Altman says she began the book with her fuzzy lip story because she wanted to reframe the shame she and the rest of us often feel about our physical selves — and lighten the taboo. She decided to face the facts — starting with a confession to her now-husband, Dave, that she does everything she can to rid herself of facial hair.”I needed him to know that he was marrying a woman with a goatee,” she says with a laugh. “I just didn’t want (1) to have him find out later and be upset, and (2) to just have to hide it anymore. I was just so tired.”Her husband’s response when Altman told him? “It’s just hair!” She says he couldn’t have cared less.INTERVIEW HIGHLIGHTS On where the idea that women should be mostly hairless comes from[Women in] the United States in the early 1900s — they were fine being hairy. But then … advertisers came on strong in the 1930s. They said that having armpit hair was dirty and gross; being clean-shaven was respectable, feminine. And then you also look at another kind of theory that we are all so afraid of our mortality; that we cover up anything that kind of hints at us being beasts, or animals. We put on perfumes, we cover up our holes — anything that excretes or is moist we don’t want anything to do with.On what it was like to grow up in a family that encouraged ‘going natural’I still had the experiences at school where I didn’t feel like I totally fit in. I was trying so hard to be natural, to be authentic like my parents said. But you still have the friends on the schoolyard who are like, ‘Ah, she’s hairy — gross!’ … I was in junior high and I was in PE class just getting ready to play dodgeball or something. And a girl pointed at my legs and said, ‘Ew, gross, you’re hairy!’ And I just felt totally seen and ashamed and wanted nothing more than to rip out every single hair on my body. And yet that went against everything in our household about being natural. And then I had to confront my mom about it, and finally ask her if I could shave.On what a psychology professor said when she asked whether premenstrual syndrome is real She said that when we say that PMS made us do something, that we’re using it as a scapegoat — and kind of discount it. And she also said that hormones don’t create moods, but they can exacerbate moods. [Those feelings are] very legitimate; we should pay attention to them. Every time we say that PMS made us do it a misogynist gets his wings! It feeds into this idea that we’re angry; that we don’t know what we’re doing. But really — like a woman who just feels really strong feelings and in another society would be extremely respected.On how she found out sweat is awesome The sweat researcher that I talked to said that if we were overheating and we couldn’t sweat, we’d basically die in, like, 20 to 30 minutes. So when I see my own sweat stains now on my pits, which is probably daily, I try to appreciate that that’s where we come from. That’s how we’re human. And I think that researching or learning about our bodies can also lessen the shame around it.On being at a nudist resort while pregnant with twins — for research You know, I wrote this book to kind of investigate why we feel the way we feel about our bodies. But a wonderful bonus was kind of realizing that we all have such a big variation. … I was like, ‘Oh my gosh! All these people. So many various sizes [and] shapes don’t fit into any of the beauty standards we typically talk about or see. There are rolls! There’s cottage cheese! There are hairy moles!’ … And they’re walking around indulging in life. And you’re like, OK, you know what? We’re just lucky we have bodies. That we get to do all this cool stuff in our bodies.Alyssa Edes and Renita Jablonksi produced and edited this interview for broadcast. Alyssa Edes adapted it for the Web. Copyright 2018 NPR. To see more, visit http://www.npr.org/.last_img read more

As nearly 75 million Americans contend with cover

first_imgAs nearly 7.5 million Americans contend with covering the skyrocketing costs of insulin to manage the disease, diabetics in Colorado will soon have some relief. A new law, signed by Gov. Jared Polis earlier this week, caps co-payments of the lifesaving medication at $100 a month for insured patients, regardless of the supply they require. Insurance companies will have to absorb the balance. The law also directs the state’s attorney general to launch an investigation into how prescription insulin prices are set throughout the state and make recommendations to the legislature. Colorado is the first state to enact such sweeping legislation aiming to shield patients from dramatic insulin price increases. “One in four type 1 diabetics have reported insulin underuse due to the high cost of insulin … [t]herefore, it is important to enact policies to reduce the costs for Coloradans with diabetes to obtain life-saving and life-sustaining insulin,” the law states. The price of the drug in the U.S. has increased exponentially in recent years. Between 2002 and 2013, it tripled, according to 2016 study published in the medical journal JAMA. It found the price of a milliliter of insulin rose from $4.34 in 2002 to $12.92 in 2013. And a March report from the House of Representatives, found “prices continued to climb, nearly doubling between 2012 and 2016.” Dramatic price hikes have left some people with Type 1 and Type 2 diabetes who use insulin to control their blood sugar levels in the unfortunate position of making dangerous compromises. They either forego the medication or they ration their prescribed dose to stretch it until they can afford the next prescription. In some instances, those compromises can lead to tragedy. As NPR reported, an uninsured Minnesota man who couldn’t afford to pay for $1,300 worth of diabetes supplies, died of diabetic ketoacidosis, according to his mother. The man, who was 26, had been rationing his insulin. The move in Colorado comes on the heels of recent commitments by manufacturers to limit the drug’s cost to consumers, which in turn comes on the heels of mounting pressure (and some skewering) from elected officials. Following a U.S. Senate Finance Committee hearing in February and a subcommittee hearing in the House in April, pharmaceutical company leaders have reluctantly admitted they have a role to play in reducing drug prices. Last month Express Scripts, one of the largest pharmacy benefit managers in the country, announced it is launching a “patient assurance program” that will place a $25 per month cap on insulin for patients “no matter what.” In March, insulin manufacturer Eli Lilly said it will soon offer a generic version of Humalog, called Insulin Lispro, at half the cost. That would drop the price of a single vial to $137.35. “These efforts are not enough,” Inmaculada Hernandez of the University of Pittsburgh School of Pharmacy tells NPR, of the latest legislation in Colorado. Hernandez was lead author of a January report in Health Affairs attributing the rising cost of prescription drugs to accumulated yearly price hikes.While the Colorado out-of-pocket caps will likely provide financial relief for diabetes patients, she noted “the costs will kick back to all of the insured population” whose premiums are likely to go up as a result.”Nothing is free,” Hernandez said.”It also doesn’t fix the real issue,” she added, pointing to her own research which found “that prices have increased because there’s not enough competition in the market, demand will always be high and manufacturers leverage that to their advantage.” Copyright 2019 NPR. To see more, visit https://www.npr.org.last_img read more

No Longer the Apple of the FBEye Start Up Your Day Roundup

first_img Add to Queue No Longer the Apple of the FB-Eye — Start Up Your Day Roundup Start Up Your Day Next Article Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Looking for the latest headlines in small business, innovation and tech? Our Start Up Your Day recaps are posted every morning to keep you current.1. No longer the Apple of the FB-EyeApple’s Tim Cook is refusing to comply with a court order to help the FBI break into the iPhone of one of the San Bernardino shooters. Apple’s tech buddies, Facebook and Twitter have declared, “I’ve got your back, Apple.”Facebook issued this statement to USA Today:  “We condemn terrorism and have total solidarity with victims of terror. Those who seek to praise, promote, or plan terrorist acts have no place on our services. We also appreciate the difficult and essential work of law enforcement to keep people safe,” the statement reads. “When we receive lawful requests from these authorities we comply. However, we will continue to fight aggressively against requirements for companies to weaken the security of their systems. These demands would create a chilling precedent and obstruct companies’ efforts to secure their products.”2. Obama and CubaPresident Obama announced via tweet on February 19 that he’s going to Cuba in March:Next month, I’ll travel to Cuba to advance our progress and efforts that can improve the lives of the Cuban people.— President Obama (@POTUS) February 18, 2016This will be the first time in 80 years a sitting president has visited Cuba, and the trip is part of Obama’s overall push to hug it out with the communist country, including opening direct flight travel between the two countries and allowing U.S. businesses to engage with Cuba.In related news, the U.S and Cuba recently sanctioned the first U.S. business since the revolution — a tractor company — to be built on Cuban soil. The business is slated to open in early 2017.3. Trump vs. the Pope“A person who thinks only about building walls, wherever they may be, and not building bridges, is not Christian,” said Pope Francis about Donald Trump’s immigration policy on wall-building and such on a return trip from Mexico, igniting a verbal smackdown from Trump who was in South Carolina rallying support before the primary.In turn, Trump called the Pope’s words “disgraceful” and added something to the effect of when ISIS comes raging on the Vatican’s door, “the pope would only wish and have prayed that Donald Trump would have been elected president.”This could be Trump’s way of saying he doesn’t need the Pope’s approval to win the Feb. 20 primary.4. Shake Shack on Delta”If someone had told me a few years ago that we’d be serving our food on an airline, I would have said over my dead body,” said Shake Shack CEO Danny Meyer to the New York Times.Airplane food isn’t exactly known for its enticing qualities, but the New York Times reported that Meyer — who runs Union Square Hospitality Group which owns Blue Smoke, Gramercy Tavern and Union Square Cafe — has teamed up with Delta Airlines to up the game of international airline food starting March 1.Now fliers of of all international first-class flights out of JFK can enjoy some foodie grub.5. Sports Illustrated swimsuit issueIt’s on newsstands. Yep.Check the site for our roundup of the most entrepreneurial models to emerge from the pages of Sports Illustrated. –shares February 19, 2016 Enroll Now for $5 4 min read Image credit: TungCheung | Shutterstock.com Carolyn Sun Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful.last_img read more

Summer Streamlining 7 Tools to Help You Automate Your Workload

first_img Opinions expressed by Entrepreneur contributors are their own. Summer Streamlining: 7 Tools to Help You Automate Your Workload 7 min read Next Article Workload Automation Guest Writer Image credit: ShutterStock July 3, 2016 Learn how to successfully navigate family business dynamics and build businesses that excel.center_img Managing partner of HigherVisibility Add to Queue –shares Free Webinar | July 31: Secrets to Running a Successful Family Business Scott Langdon It’s summer, and that means nice weather, pool parties, beach days and relaxation. Summer shouldn’t mean long days at the office, cooped up in a small space and missing all the outdoor fun. If the latter describes how you’ve been spending your time, perhaps now is a good time to start outsourcing some of your workload. Let a program do the annoying, tedious tasks your business requires to survive (and thrive), leaving you more time to enjoy summer with family and friends.Related: 4 Tools to Put a Stop to Time Wasters in 2016Workload automation might seem like a dream come true, but it’s important to understand that not every automated program is going to be right for your business. The land of workload automation is more complex now than ever, and there are an abundance of tools out there vying for the chance to handle your business tasks. So which one(s) are right for you? Read below to learn about eight of the most helpful tools in workload automation and how to use them most effectively.Social media.1. BufferBuffer is a social media marketing tool that is geared towards saving you time by connecting to various social media sites and posting on your behalf. They offer three different plans, and each includes varying amounts of assistance based on your budget and goals. As you can see below, the bigger your budget, the more you get from Buffer. But don’t feel like you need to go deep into your pockets in order to make this program a success. Their $10 a month plan still gets you 100 scheduled posts across 10 different social media accounts. Although it’s nowhere near as much as their Enterprise Plan — which also comes with analytics data — depending on the size of your business and your future goals, it might just be enough. It’s 100 less times you need to worry about making a scheduled post. This would be a very helpful tool if you’re struggling to handle a wide variety of social media accounts. If you have the extra money, the analytic data that comes with the Business and Enterprise plans could also be helpful in seeing whether or not your social media marketing is working — and thus, whether or not Buffer is a good investment.2. Sprout SocialSprout Social is another type of social media management software that works with many of the most popular social media sites out there — Facebook, Instagram, LinkedIn, Google+, Feedly, zendesk, etc. Sprout Social is different in that instead of integrating with as many profiles as possible, it focuses on quality vs. quantity. The most expensive plan only includes up to 30 profiles for $500 a month.That being said, they offer a lot more goodies for your money than Buffer does, including, but not limited to, analytic data, an all-in-one social inbox, varying types of reports, keyword tracking and message and content tracking. So again, think about your budget and your long-term goals before deciding which, if any, of these social media programs would be beneficial. Sprout Social would be great for businesses that don’t integrate with a ton of social media sites, and instead want to get the most value for the few that they do use for marketing.Related: Top 20 Social Media Tools to Add to Your Arsenal in 2016Productivity.3. IfThisThenThatIFTTT is a great way to cut down on your workload and increase productivity by creating “recipes” that utilize “if this, then that” statements. They give you an extensive list of suggestions to choose from to meet the needs of your business, home or personal life. You also have the option to customize recipes to really get the most out of this creative program. For example, you can use this site to easily and quickly create events in Google Calendar, catalog important emails using Evernote (which will also be discussed below), send reminders to yourself and/or your team, keep track of recurring tasks by scheduling to-dos and sync items across various cloud storage folders.4. TopTrackerTopTracker is a free time tracking app. Free! Who doesn’t like that? Whereas IFTTT is an app designed to increase productivity, TopTracker is designed to track your productivity in order to identify and correct deficiencies. TopTracker was made specifically with freelancers in mind. It can track activity levels and integrate timed screenshots, webcam shots or simple time tracking. It has a basic dashboard that gives you an uncluttered view of all your projects and their progress. You will also get detailed productivity reports so you know how everything is going. In addition, TopTracker gives freelancers a ton of privacy options, such as blurred screenshots and detailed privacy settings. This is a great way for small businesses to easily and privately track their productivity so they know what to improve on in the future.Organization.5. WunderlistWunderlist does exactly what their homepage boasts — it helps users keep their lives in sync by offering customized lists and reminders that you can create based off of your needs and goals. You can access Wunderlist on your phone, computer or tablet no matter where you are, making it very simple to create and keep up with all your daily, weekly and monthly tasks. You can also share your lists with friends, family and coworkers in order to collaborate on the aforementioned tasks. This would be very helpful for a business. Instead of one person slaving away on a list, you can divide and conquer with your coworkers so the work gets done more efficiently.Communication.6. InfusionsoftInfusionsoft automates your sales and marketing by combining your CRM, email marketing, lead capture and ecommerce all in one place. Their homepage boasts of the following benefits:Unfortunately, these benefits come with a price. Their cheapest plan is $199 a month and only includes CRM and marketing automation. The most expensive plan costs $599 a month and includes CRM, marketing automation, sales automation and ecommerce for up to 10 users. There’s also some plans in between that are customized for your various needs, whether they be ecommerce, sales automation or something else. There’s no doubt in my mind that Infusionsoft could help ease your workload by automating so many of your important tasks, but is the time saved worth the cost?  Weigh the pros and cons before making an investment as big as this one.Content.7. EvernoteEvernote is exactly what it sounds like — an online note-taking application that allows you to keep your thoughts, creative ideas, lists and more in a space that can be accessed from pretty much anywhere. Similar to Wunderlist, Evernote lets you keep track of photos and notes in an easy-to-find format that can also be shared with others in order to promote collaboration. Related: 4 Transformational Questions Your Business Should AskBoth offer free versions of the basic app with the option to pay to upgrade. Evernote also has a specific business option for $12 a month per user. The business version encourages teams to work together and share feedback on projects, and individuals to keep track of and sync their lists, images, files and web research all in once place.  This is a great app to use to promote working together and team-building among coworkers, which will in turn lighten everyone’s workload. Who wouldn’t be interested in that?Successful workload automation can help businesses combine both customer expectations with their business practices, resulting in happy customers and a more efficient business model. Who doesn’t want their business to operate more efficiently, especially during the summer months when there’s so much to enjoy outside of the office? Start incorporating one or more of the tools above, and you’re guaranteed to have business success, more free time and happier employees. How are you going to start?  Comment in the section below! Register Now »last_img read more

Top Email Marketing Best Practices to Increase Revenue

first_imgEmail Marketing Can Generate an ROI of over 4400%. Designrush Determined the Top Email Marketing Best Practices to Increase Revenue and the Best Email and Marketing Automation Agencies Research shows that email marketing can provide a return on investment up to 4400 percent. However, certain tactics within email campaigns will foster better revenue growth than others.DesignRush.com, a B2B marketplace connecting brands with agencies, discovered the three best email marketing best practices that can boost brands and encourage high click-through and conversion rates.The top 3 email marketing best practices of 2019 are:1. Collect Email Addresses HonestlyBrands should always ensure that the recipients of their email lists are aggregated fairly. Consumers should know exactly what they are signing up for, who is sending it, and how often they can expect emails.In addition, businesses should avoid tactics such as buying email lists. Although those might initially boost the number of people who receive communications, brands will also likely see lower click-through rates and conversions, and higher unsubscribe rates.Marketing Technology News: Contact Centers Adding AI to Become More Intelligent, Responsive to Customers2. Write Engaging Subject Lines Without Looking Like SpamThe key to increasing open rates – which is essentially the first step to email-driven conversions – is to write buzz-worthy subject lines. These should concisely describe the contents of the email and the unique value added. For instance, eCommerce stores should highlight sale details, while news organizations should focus on breaking news.However, too many buzz words can look like spam to inboxes – causing messages to go straight to spam – and recipients – causing them to delete the email. Avoid elements such as all capital letters and too many emojis in subject lines.3. A/B TestEach brand will find that certain email strategies work better for them than others – and no two brands are exactly the same. Therefore, the best way to understand the content and email tactics that a target audience wants is to A/B test campaigns.To do so, brands send two email campaigns that are exactly the same save for one element – such as delivery time, subject line, content format, or something else. A randomized half of their email list will receive one, and the other will receive the test campaign. Then, brands can compare results to determine which tactic was the most effective.“Email is one of the most effective – and trackable – forms of digital marketing,” says DesignRush Founder and Executive Director Gabriel Shaoolian. “By implementing a few best practices, brands will be able to sharpen their email campaigns, improve overall success, and grow their businesses and revenue more effectively.”Marketing Technology News: PX Open Marketplace Surpasses 500 Publishers in its ExchangeDesignRush’s Agency Listing section features the top local and global email marketing companies. The top email and marketing automation agencies include:1. B2B Data GuyB2B Data Guy is a one-stop shop for B2B email lists and managed email campaigns. All contacts are verified deliverable, and if an email bounces its refunded. B2B Data Guy boasts average open rates 62%, varies by industry, lists delivered within 72 hours of payment, discounts for orders over 1,000 contacts and for repeat orders, 36 data points per contact, amazing customer service, and email campaign creation/support help available upon request.2. BestSEO4uBestSEO4u is an online marketing agency which stands proudly among the leading specialist UK WordPress agencies and is a trusted Internet Marketing expert. To them, online success doesn’t mean just traffic – it translates to top conversion rates and earnings. Their experience and portfolio recommend them as the dynamic, flexible, innovative and reliable partner each online business has always needed. Their London-based company is at the heart of everything – they’re among thriving businesses in a most competitive environment, where players are always on the look for the next best strategy. Nothing better for them, as it allows BestSEO4u to improve their game consistently and deliver outstanding solutions to clients!3. Black87Black87 is the team of inspired, ambitious and creative fellows. Their performance marketing services are designed for brands to have full control over their marketing spending. They can help brands own their piece of the web. Driving measurable results, Black87’s forward-looking approach has helped clients in technology, physical retail, e-commerce, and crowdfunding projects.Marketing Technology News: Pagely Announces 2nd Annual Scholarship for Underrepresented Students in Tech Top Email Marketing Best Practices to Increase Revenue PRNewswireApril 25, 2019, 4:00 pmApril 25, 2019 A/B testb2b marketplacecrowdfunding projectsemail marketingmarketing automationMarketing TechnologyNews Previous Article9 out of 10 Marketers Deploy Personalization to Improve Customer Experiences, According to New Evergage StudyNext ArticleData-Driven Marketers Head to the Cloudlast_img read more

Introducing Shutterstock Elements Thousands of CinemaGrade Video Effects for Filmmakers

first_img NewsShutterstockVideo Previous ArticleGCOM Software Announces Ernie Connon as New Chief Growth OfficerNext ArticleProgress Named a Leader in the New 2019 Gartner Magic Quadrant for Multiexperience Development Platforms Introducing Shutterstock Elements, Thousands of Cinema-Grade Video Effects for Filmmakers MTS Staff WriterJuly 16, 2019, 10:35 pmJuly 16, 2019 Blockbuster-quality video effects created by industry professionals, including 4K lens flares, essential transitions, captivating video kits with smoke, fire, explosions and moreShutterstock, Inc., a leading global technology company offering a creative platform for high-quality content, tools and services, announced its new footage offering—Shutterstock Elements. Over 3,000 elements captured on cinema-grade cameras and lenses have been added to the site, including transitions, lens flares, VFX (visual effects), video kits, film overlays, HUD (head-up display) and UI (user interface) elements. Compatible with all major video editing programs, Elements also includes detailed tutorials on how to optimize effects.Video consumption rates continue to grow and consequently, the power of video content has never been stronger. According to Mary Meeker’s 2019 Internet Trends Report, digital video is now up to 28% of average daily watching time and 59% of Gen Z users cite YouTube as their preferred learning channel. As marketers respond to this trend by making video a top priority in their marketing mix, Shutterstock Elements offers popular, easy-to-use video effects that anyone can apply to make their content stand out.Marketing Technology News: Introducing Acoustic: A New Marketing Cloud Bringing Humanity to AI-Powered Marketing“The demand for high-quality video is growing while budgets are only getting smaller and timelines are getting shorter. Video editors, compositors, and vloggers are constantly faced with the challenge of maintaining quality and making the content stand out in today’s golden age of video,” said Sylvain Grande, SVP of Product & UX at Shutterstock. “Elements is a one-stop shop for creatives who are churning out projects at an unprecedented rate, providing assets made with cinema-grade equipment that can make any project look like a big-budget production in no time.”The new offering includes expertly curated categories for specific genres, from content for everyday moments to blockbuster action scenes. Video kits like “Yum” are tailored for food vloggers and How-to’s with over 100 elements including lower thirds, transitions, animated characters, and loopable backgrounds. Film overlays like “Illuminate” offer 120 different light leak elements and practical effects shot in 4K resolution. The curated collections are designed to take any video project to the next level by adding polished elements and finishing touches like flares and sizzle for a more professional feel.Marketing Technology News: New TimeTrade Schedule-A-Demo Solution Helps B2B Software Companies Increase Inbound Lead-to-Meeting Conversion by 4XThe wide selection of elements ranges from digital assets, like transitions and overlays, to physical effects like explosions or glass shattering. The physical assets were each filmed on location with specialists using high-end gear—like the Ricochet VFX pack, which includes authentic muzzle flashes filmed working alongside experts, or the Detonate VFX pack which offers explosions as wide 250 feet.Marketing Technology News: Blue Prism Collaborates with Microsoft to Deliver Free Cloud Trial on Azurelast_img read more

Progress in meningitis lags far behind other vaccinepreventable diseases analysis shows

first_imgNov 15 2018Wider vaccine protection and improved diagnosis and treatment needed to control global cases of meningitisThe global disease burden of meningitis remains unacceptably high, and progress lags substantially behind that of other vaccine-preventable diseases, warns a new analysis published in The Lancet Neurology.The Institute for Health Metrics and Evaluation (IHME) Global Burden of Disease study showed that meningitis deaths reduced by just 21% globally between 1990 – 2016, whereas other preventable diseases such as measles, tetanus, and diarrhea due to rotavirus saw declines of 93.0%, 90.7%, and 57.9%, respectively, suggesting that progress in meningitis could have been substantially faster.The number of actual cases of meningitis increased during that time period, from 2.5 million in 1990 to 2.82 million in 2016, due to increased population size.The highest concentration of cases and deaths from meningitis was found in the sub-Saharan African countries that are collectively known as the “meningitis belt”. This is despite huge progress in reducing meningococcal group A disease by 99% in the meningitis belt through the MenAfriVac vaccination program.Meningitis Research Foundation, co-authors of the analysis, state that to make faster progress, particular attention should be given to: developing vaccines with broader coverage against the bacterial causes of meningitis; making these vaccines affordable to the developing countries that are most affected; improving vaccine uptake; and improving interventions such as access to low-cost, rapid diagnostic tests and treatments.Ongoing surveillance of the specific types of bacteria causing meningitis is said to be crucial to continue monitoring and reacting to meningitis burdens and trends throughout the world.Bacterial meningitis is a deadly disease that strikes without warning and can leave survivors with lifelong after effects as serious as deafness, blindness and brain damage. The paper states that better support for disabled or impaired survivors of this disease is vital.IHME’s Dr. Nicholas J. Kassebaum, Professor of Health Metrics Sciences with the University of Washington, commented: Declines in the incidence and mortality of meningitis have lagged far behind those of other vaccine-preventable diseases, such as diarrhea and lower respiratory infections. It is likely that the growing number of meningitis survivors with lifelong disabilities are living in communities without the resources or programs to support them.” Source:https://www.meningitis.org/news/meningitis-progress-could-have-been-faster This research shows that a huge number of people are still being affected by this dreadful disease. Vaccination is the only way to prevent meningitis and despite major progress over the last 20 years, large epidemics have occurred recently showing again that meningitis is very far from being defeated. “Meningitis spreads around the world and we need a coordinated effort to defeat it. We need faster progress, similar to that achieved with measles, tetanus, and diarrhea due to rotavirus. This year the World Health Organization launched an expert taskforce to develop a global roadmap to defeat meningitis by 2030, and MRF is delighted to be taking part. This taskforce is a crucial step towards defeating meningitis for good.” Study author Linda Glennie from Meningitis Research Foundation said:last_img read more

Study follows children into adolescence to more accurately assess type 1 diabetes

first_img Source:http://www.augusta.edu/mcg/ Reviewed by James Ives, M.Psych. (Editor)Jan 3 2019Scientists are narrowing in on checklists of both errant genes and the environmental factors that could trigger those genes to more accurately assess type 1 diabetes risk and help children and their families avoid it.”The next five years is the time to put the puzzle together,” says Dr. Jin-Xiong She, director of the Center for Biotechnology and Genomic Medicine at the Medical College of Georgia at Augusta University and Georgia Research Alliance Eminent Scholar in Genomic Medicine.She is talking about the TEDDY – The Environmental Determinants of Diabetes in the Young – study that started in 2003 at MCG and five other clinical centers across four countries and is following nearly 9,000 children and their families. She is principal investigator for studies in Georgia and Florida. TEDDY also has clinical centers in Colorado, Washington, Finland, Sweden and Germany.”This will enable us to continue working with families, collecting and analyzing samples and data, for the next five years,” says She, who recently received a $3 million grant from the National Institutes of Health to continue his part of the studies in two of the most populous and fastest-growing states in the nation.He’s optimistic that the unprecedented, prospective study documenting how genes and environment collide to cause a condition that typically surfaces in youth and destroys the insulin-producing beta cells in the pancreas, will enable prevention of the condition that affects about 1 in 300 by age 18, according to the NIH.Today there is no proven way to prevent type 1 diabetes, which hits at the heart of what TEDDY is about, She says.Two peak ages ranges for type 1 diabetes are 2-4 and 12-15 and since TEDDY began, parents have been keeping exhaustive diaries on everything from a well-baby visit to the doctor to vaccinations to over-the-counter drugs the children take. They also collect nail, stool and blood samples throughout the 15-years each child is being followed. Scientists have been analyzing it all, including the water children drink, which can vary from one metropolis to the next. The international scope of the study is enabling identification of even regional differences that may be factors in disease development.The massive data that continues to be generated by some 9,000 TEDDY families is yielding previously unknown high-risk genes and environmental factors that will ultimately lead to those genetic and environmental checklists.”How to predict risk is an important question, but the main question of TEDDY is what can we do about that risk?” She says. Ideally that will mean keeping the immune system of high-risk children from ever making autoantibodies against their insulin producing cells. That means screening should start early, probably within the first year of life, She says, possibly even as one of the blood tests done for newborns.Next year, TEDDY participants start turning 15; right now, the average age is about 11. TEDDY investigators project about 450 children will be persistently autoantibody positive as they reach adolescence. TEDDY investigators would like to follow those children at least into adulthood.The Georgia-Florida TEDDY contingent She leads includes about 600 children. To date 22 children have developed type 1 diabetes and another 58 are autoantibody positive. He suspects by the end of the next five years, about half those children will also have the disease.Autoantibodies are evidence that the child’s immune system has started to target the child’s insulin producing cells. It’s the attack and eventual destruction of the beta cells by the immune system that leave children dependent on insulin therapy the rest of their lives.To date about 12 percent of TEDDY children had autoantibodies by age 10 and nearly 8 percent have multiple antibodies.But in some young children, autoantibodies disappear and now TEDDY scientists are looking at whether autoantibodies reappear when those children reach adolescence and what factors are associated with recurrence versus remission. They also are looking at which autoantibodies are associated with slow versus rapid progression to full-blown type 1 diabetes. About 10 percent of children who develop autoantibodies don’t develop disease and those children likely hold insight as well.They suspect over the next five years as children age and more develop autoantibodies and/or disease, they’ll find the triggering environmental factors will change as well, another reason investigators says five more years of monitoring is important.Technological advances that have occurred over the life of TEDDY also now mean they can monitor advancement from a single to multiple autoantibodies to full-blown disease. Parallel environmental exposures over that timeframe already are providing more insight into causes and logical points for intervention.Related StoriesWhy Mattresses Could be a Health Threat to Sleeping ChildrenRepurposing a heart drug could increase survival rate of children with ependymomaResearchers identify gene mutations linked to leukemia in children with Down’s syndromeTo first enroll study participants, TEDDY screened for two known high-risk genes out of the handful of genes known at that time. Children with those genes – and no first-degree relative with the disease – have about a 3 percent disease risk, 10 times higher than children without those genes. Those with the genes and a first- degree relative with type 1 have about a 14 percent chance of developing type 1 diabetes. Identifying more high-risk genes should significantly improve the ability to identify risk, She says.TEDDY has helped identify multiple additional high-risk genes with more to come, he says, and future screens will likely look at a few hundred genes.”We are working on a new test that may analyze hundreds of genes that we think will be more accurate, more predictive,” She says.He says parallel general prevention strategies likely won’t result, rather precision strategies based on a child’s genetic, social, cultural, ethnic and geographical parameters.Environmental factors include dietary triggers, so the scientists are now following up on observations already made in TEDDY like the fact that adequate vitamin D levels are associated with lower risk of type 1 diabetes particularly in children with even one minor genetic variation on their vitamin D receptor gene. They’ve also found that exposure to probiotics in infancy decreases diabetes development risk in the highest risk children while consuming hydrolyzed infant formula – which is considered hypoallergenic and good for infants who can’t digest cow milk – increases risk.Scientists anticipate these additional years of study will enable dietary interventions to emerge that help prevent disease development.They also are looking further at the psychosocial impact of the study itself as well as the disease on parents and children. TEDDY families experiencing maladjustments are offered counseling and the investigators already have noted issues such as: increased parent anxiety when an autoantibody is detected; parents who still underestimate the full impact of the disease; and parents who pursue unproven methods to prevent type 1 diabetes development.Now that at-risk children are older, they can also talk with them about the emotional and behavioral impact, and look for signs of stress like presence of the stress hormone cortisol in their toenail clippings.They also are generating data on the physical activity of the TEDDY participants and keeping measures of their body composition to explore how they might affect risk of developing autoantibodies and progression to type 1 diabetes.While weight and inactivity are considered major risk factors for type 2 diabetes, “How much it contributes to type 1, we don’t know,” says She. “That is why we are looking, and in the next five years, we will be able to give you an answer.”They also are following the children for development of related autoimmune diseases like celiac disease and autoimmune thyroid disease. About 9 percent of TEDDY participants, for example, have developed both celiac disease and type 1 diabetes. Autoimmune thyroid disease has genetic risk factors similar to type 1 diabetes, She says. “They are enriched in the TEDDY population, so we also want to identify those at high risk for autoimmune thyroid disease,” She says. That likely means also developing better screening for these conditions, which often surface much later in life. In fact, the thyroid is the most common organ affected by autoimmune disease.She and TEDDY research manager Diane Hopkins regularly laud the TEDDY families for their extraordinary commitment to the long, extensive study and recently hosted a party for about 300 TEDDY families from the two-state area they manage. Attrition has been low and some families even came back after dropping out, She notes.”They want to help us better understand what is happening and they want to know what is happening,” She says. “They have become part of the extended family.”The TEDDY consortium includes collaborators and principal investigators at Morsani College of Medicine at the University of South Florida; Pacific Northwest Research Institute in Seattle; Sweden’s Lund University; the University of Colorado; Germany’s Helmholtz Zentrum München and Klinikum rechts der Isar, Technische Universit? München and Forschergruppe Diabetes e.V.; and Finland’s University of Turku and Turku University Hospital. Data generated by TEDDY is available to all scientists.Type 1 diabetes can affect the entire body, cause heart and blood vessel disease, kidney, eye and foot damage and nerve damage. It generally reduces life expectancy by about a decade.last_img read more

Ebola spread to Uganda could threaten international health

first_img What is Ebola? Ebola Virus Epidemiology Ebola Virus Symptoms Ebola Virus Diagnosis and Treatment Ebola Virus Prevention Ebola Research Related StoriesNovel vaccine against bee sting allergy successfully testedScripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approachNew shingles vaccine reduces outbreaks of painful rash among stem cell transplant patientsOther contacts have been identified, and advised to remain at home to be vaccinated against the disease. Uganda is in a state of Ebola alert, which was initiated since the DRC outbreak began. There have been no mass gatherings, and information about the disease is being broadcast continuously. Almost 4,000 health workers have received vaccination, and screening camps are operating all along the border with DRC, and other major portals. Places at high risk because of high people mobility and proximity to the border are being monitored constantly for spot diagnosis and management of any cases.Uganda will begin ring immunization on June 14 to contain the spread of the virus by immunizing direct contacts and their contacts. A rapid response team is already in place to identify those at high risk. 400 doses of Ebola vaccine have been sent in by the DRC with another 4,000 doses from the WHO. This new vaccine prevents infection in almost 98% of cases.The WHO Emergency Committee will also sit for the third time to decide whether to declare the DRC outbreak a “public health emergency of international concern,” or PHEIC, which will attract international help in dealing with it.The DRC epidemic began in August 2018, with almost 2,100 cases so far and counting. Civil conflicts have made it difficult to control the illness, with approximately 200 medical facilities being attacked on several occasions this year. As a result, health workers have been forced to suspend operations in some centers where the disease is raging. Despite this, WHO has not declared it a PHEIC so far.Other countries are taking their own precautions. Rwanda has already decided to police its borders, and its people are being exhorted to stay away from virus-rife areas. Vaccination is being promoted among health workers who come in contact with possible contacts.Ebola is primarily an animal disease, with the virus taking shelter in bats and other mammals. It may spill over into the human population when someone eats an infected bat, for instance. However, such events usually end spontaneously with a chain of not more than 5 people. The DRC outbreak is the second largest ever recorded and the worst ever in this country.The first Ugandan case reported on June 11 was a 5-year old boy whose grandfather in DRC had just died of Ebola. His Ugandan family, who had crossed the border to care for their father, returned home just a few days before the boy fell sick, followed by two others. Two of them died shortly afterwards. The remaining family members were given passage back over the border, while several other contacts with high fever, also from the DRC, were put in isolation. However, many of them absconded from the treatment center. Ebola viruses in blood of a patient with Ebola hemorrhagic fever, 3D illustration – Illustration Credit: Designua / Shutterstock Surveillance for ebola virus disease at the border between DR Congo and Uganda | Photo: Matt Taylor Researcher Emma Glennon modeled the size of likely distributions using available datasets on Ebola outbreaks from three countries in West Africa. She found that compared to the reported size of the outbreak in these places, only about 17% to 48% were actually reported. In other words, about half of all outbreaks are never reported. When it comes to single cases of infection, dying out without spreading any further, the chances of detection are below 10%. Glennon remarks, “Early detection of outbreaks is critical to timely response, but estimating detection rates is difficult because unreported spillover events and outbreaks do not generate data.”This research points to the importance of identifying outbreaks as early as possible before many people are infected. However, it also explains why many people in these countries show the presence of antibodies to Ebola. Clinically recognized outbreaks include only symptomatic cases, and if over 80% of single cases or small outbreaks are missed, this could be the reason for the presence of these antibodies, says Ian Mackay, at the University of Queensland in Australia. By Dr. Liji Thomas, MDJun 14 2019After smouldering in the Democratic Republic of Congo (DRC) for almost a year, killing near 1,000 people, the deadly Ebola virus crossed the border to Uganda in June 2019. This virus causes sudden high fever and sore throat, with severe weakness and muscle pain. It quickly progresses to vomiting and diarrhea, with signs of internal and external bleeding. It is transmitted through contact with body fluid from an infected person. The fatality rate is high. Further Reading Source: Confirmation of case of ebola virus disease in Uganda, https://afro.who.int/news/confirmation-case-ebola-virus-disease-ugandalast_img read more